MERLIN PROJECT MANAGEMENT REVIEW 2011 MANUAL
MERLIN PROJECT MANAGEMENT REVIEW 2011 FULL

This section describes post-translational modifications (PTMs) and/or processing / Processing i Molecule processing Feature key

Pharos NIH Druggable Genome Knowledgebase More.Pharos iД«ioMuta curated single-nucleotide variation and disease association database More.BioMuta iДomain mapping of disease mutations (DMDM) More.DMDM i The Pharmacogenetics and Pharmacogenomics Knowledge Base More.PharmGKB i Orphanet a database dedicated to information on rare diseases and orphan drugs More.Orphanet iДў495п»ї, Meningioma 637п»ї, Neurofibromatosis type 2 93921п»ї, Schwannomatosis MalaCards human disease database More.MalaCards iДЎ01000п»ї, phenotype 156240п»ї, phenotype 162091п»ї, phenotype GeneReviews a resource of expert-authored, peer-reviewed disease descriptions. Keywords - Disease i Deafness, Disease variant, Tumor suppressor Organism-specific databases

MERLIN PROJECT MANAGEMENT REVIEW 2011 MANUAL

Manual assertion based on experiment in iД¬ited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH DCAF1 AND THE CUL4A-RBX1-DDB1-VPRBP/DCAF1 E3 UBIQUITIN-PROTEIN LIGASE COMPLEX, PHOSPHORYLATION, MUTAGENESIS OF LEU-64 AND SER-518, CHARACTERIZATION OF VARIANT ARG-46, CHARACTERIZATION OF VARIANTS NF2 SER-62 AND PRO-141. This subsection of the 'Sequence' section describes natural variant(s) of the protein variant i VAR_000810ДЇ в†’ S in NF2 loss of ability to interact with the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. Although the tumors of NF2 are histologically benign, their anatomic location makes management difficult, and patients suffer great morbidity and mortality. Affected individuals generally develop symptoms of eighth-nerve dysfunction in early adulthood, including deafness and balance disorder.

MERLIN PROJECT MANAGEMENT REVIEW 2011 FULL

It is inherited in an autosomal dominant fashion with full penetrance. NeXtProt the human protein knowledge platform More.neXtProt iД®ukaryotic Pathogen, Vector and Host Database Resources More.VEuPathDB iДisease descriptionGenetic disorder characterized by bilateral vestibular schwannomas (formerly called acoustic neuromas), schwannomas of other cranial and peripheral nerves, meningiomas, and ependymomas. Online Mendelian Inheritance in Man (OMIM) More.MIM i Human Gene Nomenclature Database More.HGNC i

of a set of proteins thought to be expressed by organisms whose genomes have been completely iДЄ UniProt proteome can consist of several components.The component name refers to the genomic component encoding a set of proteins.More. This subsection of the Names and taxonomy section is present for entries that are part of a proteome, i.e. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed lineage iД¬ellular organisms вЂє Eukaryota вЂє Opisthokonta вЂє Metazoa вЂє Eumetazoa вЂє Bilateria вЂє Deuterostomia вЂє Chordata вЂє Craniata вЂє Vertebrata вЂє Gnathostomata вЂє Teleostomi вЂє Euteleostomi вЂє Sarcopterygii вЂє Dipnotetrapodomorpha вЂє Tetrapoda вЂє Amniota вЂє Mammalia вЂє Theria вЂє Eutheria вЂє Boreoeutheria вЂє Euarchontoglires вЂє Primates вЂє Haplorrhini вЂє Simiiformes вЂє Catarrhini вЂє Hominoidea вЂє Hominidae вЂє Homininae вЂє Homo This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism.

This is known as the 'taxonomic identifier' or 'taxid'.More.Taxonomic identifier i This subsection of the Names and taxonomy section shows the unique identifier assigned by the NCBI to the source organism of the protein. This subsection of the Names and taxonomy section provides information on the name(s) of the organism that is the source of the protein i

Merlin project management review 2011